Cargando…

Siponimod ameliorates metabolic oligodendrocyte injury via the sphingosine-1 phosphate receptor 5

Multiple sclerosis (MS), an autoimmune-driven, inflammatory demyelinating disease of the central nervous system (CNS), causes irreversible accumulation of neurological deficits to a variable extent. Although there are potent disease-modifying agents for its initial relapsing–remitting phase, immunos...

Descripción completa

Detalles Bibliográficos
Autores principales: Behrangi, Newshan, Heinig, Leo, Frintrop, Linda, Santrau, Emily, Kurth, Jens, Krause, Bernd, Atanasova, Dimitrinka, Clarner, Tim, Fragoulis, Athanassios, Joksch, Markus, Rudolf, Henrik, Meuth, Sven G., Joost, Sarah, Kipp, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546621/
https://www.ncbi.nlm.nih.gov/pubmed/36161894
http://dx.doi.org/10.1073/pnas.2204509119