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Siponimod ameliorates metabolic oligodendrocyte injury via the sphingosine-1 phosphate receptor 5
Multiple sclerosis (MS), an autoimmune-driven, inflammatory demyelinating disease of the central nervous system (CNS), causes irreversible accumulation of neurological deficits to a variable extent. Although there are potent disease-modifying agents for its initial relapsing–remitting phase, immunos...
Autores principales: | Behrangi, Newshan, Heinig, Leo, Frintrop, Linda, Santrau, Emily, Kurth, Jens, Krause, Bernd, Atanasova, Dimitrinka, Clarner, Tim, Fragoulis, Athanassios, Joksch, Markus, Rudolf, Henrik, Meuth, Sven G., Joost, Sarah, Kipp, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546621/ https://www.ncbi.nlm.nih.gov/pubmed/36161894 http://dx.doi.org/10.1073/pnas.2204509119 |
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