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CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy

The mammalian cryptochrome isoforms, CRY1 and CRY2, are core circadian clock regulators that work redundantly. Recent studies revealed distinct roles of these closely related homologs in clock output pathways. Isoform-selective control of CRY1 and CRY2 is critical for further understanding their red...

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Detalles Bibliográficos
Autores principales: Miller, Simon, Kesherwani, Manish, Chan, Priscilla, Nagai, Yoshiko, Yagi, Moeri, Cope, Jamie, Tama, Florence, Kay, Steve A., Hirota, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546630/
https://www.ncbi.nlm.nih.gov/pubmed/36161947
http://dx.doi.org/10.1073/pnas.2203936119