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CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy
The mammalian cryptochrome isoforms, CRY1 and CRY2, are core circadian clock regulators that work redundantly. Recent studies revealed distinct roles of these closely related homologs in clock output pathways. Isoform-selective control of CRY1 and CRY2 is critical for further understanding their red...
Autores principales: | Miller, Simon, Kesherwani, Manish, Chan, Priscilla, Nagai, Yoshiko, Yagi, Moeri, Cope, Jamie, Tama, Florence, Kay, Steve A., Hirota, Tsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546630/ https://www.ncbi.nlm.nih.gov/pubmed/36161947 http://dx.doi.org/10.1073/pnas.2203936119 |
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