TFG regulates secretory and endosomal sorting pathways in neurons to promote their activity and maintenance

Molecular pathways that intrinsically regulate neuronal maintenance are poorly understood, but rare pathogenic mutations that underlie neurodegenerative disease can offer important insights into the mechanisms that facilitate lifelong neuronal function. Here, we leverage a rat model to demonstrate d...

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Detalles Bibliográficos
Autores principales: Peotter, Jennifer L., Pustova, Iryna, Lettman, Molly M., Shatadal, Shalini, Bradberry, Mazdak M., Winter-Reed, Allison D., Charan, Maya, Sharkey, Erin E., Alvin, James R., Bren, Alyssa M., Oie, Annika K., Chapman, Edwin R., Salamat, M. Shahriar, Audhya, Anjon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546632/
https://www.ncbi.nlm.nih.gov/pubmed/36161950
http://dx.doi.org/10.1073/pnas.2210649119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546632/
https://www.ncbi.nlm.nih.gov/pubmed/36161950
http://dx.doi.org/10.1073/pnas.2210649119

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