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Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity

SARS-CoV-2 spike (S) protein mediates virus attachment to the cells and fusion between viral and cell membranes. Membrane fusion is driven by mutual interaction between the highly conserved heptad-repeat regions 1 and 2 (HR1 and HR2) of the S2 subunit of the spike. For this reason, these S2 regions...

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Detalles Bibliográficos
Autores principales: Cano-Muñoz, Mario, Polo-Megías, Daniel, Cámara-Artigas, Ana, Gavira, José A., López-Rodríguez, María J., Laumond, Géraldine, Schmidt, Sylvie, Demiselle, Julien, Bahram, Seiamak, Moog, Christiane, Conejero-Lara, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546781/
https://www.ncbi.nlm.nih.gov/pubmed/36220405
http://dx.doi.org/10.1016/j.ijbiomac.2022.10.031