Marker-free co-selection for successive rounds of prime editing in human cells

Prime editing enables the introduction of precise point mutations, small insertions, or short deletions without requiring donor DNA templates. However, efficiency remains a key challenge in a broad range of human cell types. In this work, we design a robust co-selection strategy through coediting of...

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Detalles Bibliográficos
Autores principales: Levesque, Sébastien, Mayorga, Diana, Fiset, Jean-Philippe, Goupil, Claudia, Duringer, Alexis, Loiselle, Andréanne, Bouchard, Eva, Agudelo, Daniel, Doyon, Yannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546848/
https://www.ncbi.nlm.nih.gov/pubmed/36207338
http://dx.doi.org/10.1038/s41467-022-33669-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546848/
https://www.ncbi.nlm.nih.gov/pubmed/36207338
http://dx.doi.org/10.1038/s41467-022-33669-z

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