The ataxia-linked E1081Q mutation affects the sub-plasma membrane Ca(2+)-microdomains by tuning PMCA3 activity

Calcium concentration must be finely tuned in all eukaryotic cells to ensure the correct performance of its signalling function. Neuronal activity is exquisitely dependent on the control of Ca(2+) homeostasis: its alterations ultimately play a pivotal role in the origin and progression of many neuro...

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Detalles Bibliográficos
Autores principales: Vallese, Francesca, Maso, Lorenzo, Giamogante, Flavia, Poggio, Elena, Barazzuol, Lucia, Salmaso, Andrea, Lopreiato, Raffaele, Cendron, Laura, Navazio, Lorella, Zanni, Ginevra, Weber, Yvonne, Kovacevic-Preradovic, Tatjana, Keren, Boris, Torraco, Alessandra, Carrozzo, Rosalba, Peretto, Francesco, Peggion, Caterina, Ferro, Stefania, Marin, Oriano, Zanotti, Giuseppe, Calì, Tito, Brini, Marisa, Carafoli, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546857/
https://www.ncbi.nlm.nih.gov/pubmed/36207321
http://dx.doi.org/10.1038/s41419-022-05300-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546857/
https://www.ncbi.nlm.nih.gov/pubmed/36207321
http://dx.doi.org/10.1038/s41419-022-05300-y

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