Multivalent binding kinetics resolved by fluorescence proximity sensing

Multivalent protein interactors are an attractive modality for probing protein function and exploring novel pharmaceutical strategies. The throughput and precision of state-of-the-art methodologies and workflows for the effective development of multivalent binders is currently limited by surface imm...

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Detalles Bibliográficos
Autores principales: Schulte, Clemens, Soldà, Alice, Spänig, Sebastian, Adams, Nathan, Bekić, Ivana, Streicher, Werner, Heider, Dominik, Strasser, Ralf, Maric, Hans Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546861/
https://www.ncbi.nlm.nih.gov/pubmed/36207490
http://dx.doi.org/10.1038/s42003-022-03997-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546861/
https://www.ncbi.nlm.nih.gov/pubmed/36207490
http://dx.doi.org/10.1038/s42003-022-03997-3

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