Cargando…
Multivalent binding kinetics resolved by fluorescence proximity sensing
Multivalent protein interactors are an attractive modality for probing protein function and exploring novel pharmaceutical strategies. The throughput and precision of state-of-the-art methodologies and workflows for the effective development of multivalent binders is currently limited by surface imm...
Autores principales: | Schulte, Clemens, Soldà, Alice, Spänig, Sebastian, Adams, Nathan, Bekić, Ivana, Streicher, Werner, Heider, Dominik, Strasser, Ralf, Maric, Hans Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546861/ https://www.ncbi.nlm.nih.gov/pubmed/36207490 http://dx.doi.org/10.1038/s42003-022-03997-3 |
Ejemplares similares
-
Encodings and models for antimicrobial peptide classification for multi-resistant pathogens
por: Spänig, Sebastian, et al.
Publicado: (2019) -
Unsupervised encoding selection through ensemble pruning for biomedical classification
por: Spänig, Sebastian, et al.
Publicado: (2023) -
A parametric approach for molecular encodings using multilevel atomic neighborhoods applied to peptide classification
por: Hattab, Georges, et al.
Publicado: (2023) -
A large-scale comparative study on peptide encodings for biomedical classification
por: Spänig, Sebastian, et al.
Publicado: (2021) -
Junction resolving enzymes use multivalency to keep the Holliday junction dynamic
por: Zhou, Ruobo, et al.
Publicado: (2019)