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Optimization of spin-lock times for T(1ρ) mapping of human knee cartilage with bi- and stretched-exponential models

Two optimization criteria based on Cramér-Rao Bounds are compared between each other and with non-optimized schedules for T(1ρ) mapping using synthetic data, model phantoms, and in-vivo knee cartilage. The curve fitting is done on complex-valued data using an iterative Nonlinear Least Squares (NLS)...

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Detalles Bibliográficos
Autores principales: de Moura, Hector L., Menon, Rajiv G., Zibetti, Marcelo V. W., Regatte, Ravinder R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546896/
https://www.ncbi.nlm.nih.gov/pubmed/36207361
http://dx.doi.org/10.1038/s41598-022-21269-2