Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity

Whether a small GTPase RhoA plays a role in the pathology of abdominal aortic aneurysm (AAA) has not been determined. We show here that RhoA expression is reduced in human AAA lesions, compared with normal areas. Furthermore, incidence of AAA formation is increased in vascular smooth muscle cell (VS...

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Detalles Bibliográficos
Autores principales: Molla, Md Rasel, Shimizu, Akio, Komeno, Masahiro, Rahman, Nor Idayu A., Soh, Joanne Ern Chi, Nguyen, Le Kim Chi, Khan, Mahbubur Rahman, Tesega, Wondwossen Wale, Chen, Si, Pang, Xiaoling, Tanaka-Okamoto, Miki, Takashima, Noriyuki, Sato, Akira, Suzuki, Tomoaki, Ogita, Hisakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546906/
https://www.ncbi.nlm.nih.gov/pubmed/36207400
http://dx.doi.org/10.1038/s42003-022-04042-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546906/
https://www.ncbi.nlm.nih.gov/pubmed/36207400
http://dx.doi.org/10.1038/s42003-022-04042-z

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