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Retrospective study for the universal applicability of the residue-based linear free energy relationship in the two-state exchange of protein molecules
Multiprobe measurements, such as NMR and hydrogen exchange studies, can provide the equilibrium constant, K, and rate constants for forward and backward processes, k and k′, of the two-state structural changes of a polypeptide on a per-residue basis. We previously found a linear relationship between...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546931/ https://www.ncbi.nlm.nih.gov/pubmed/36207470 http://dx.doi.org/10.1038/s41598-022-21226-z |