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Search and processing of Holliday junctions within long DNA by junction-resolving enzymes

Resolution of Holliday junctions is a critical intermediate step of homologous recombination in which junctions are processed by junction-resolving endonucleases. Although binding and cleavage are well understood, the question remains how the enzymes locate their substrate within long duplex DNA. He...

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Detalles Bibliográficos
Autores principales: Kaczmarczyk, Artur P., Déclais, Anne-Cécile, Newton, Matthew D., Boulton, Simon J., Lilley, David M. J., Rueda, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547003/
https://www.ncbi.nlm.nih.gov/pubmed/36207294
http://dx.doi.org/10.1038/s41467-022-33503-6