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Combined anti-tumor efficacy of somatostatin fusion protein and vaccinia virus on tumor cells with high expression of somatostatin receptors

Somatostatin, a growth hormone-release inhibiting peptide, exerts antiproliferative and antiangiogenic effects on tumor cells. However, the short half-life of somatostatin limits its application in human therapy, and long-acting somatostatin fusion protein is also limited by its severe terminal degr...

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Detalles Bibliográficos
Autores principales: Fan, Jun, Deng, Lili, Peng, Ying, Ding, Yuedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547013/
https://www.ncbi.nlm.nih.gov/pubmed/36207478
http://dx.doi.org/10.1038/s41598-022-21506-8