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Mechanoresponsive regulation of fibroblast-to-myofibroblast transition in three-dimensional tissue analogues: mechanical strain amplitude dependency of fibrosis

The spatiotemporal interaction and constant iterative feedback between fibroblasts, extracellular matrix, and environmental cues are central for investigating the fibroblast-induced musculoskeletal tissue regeneration and fibroblast-to-myofibroblast transition (FMT). In this study, we created a fibr...

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Detalles Bibliográficos
Autores principales: Jacho, Diego, Rabino, Agustin, Garcia-Mata, Rafael, Yildirim-Ayan, Eda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547073/
https://www.ncbi.nlm.nih.gov/pubmed/36207437
http://dx.doi.org/10.1038/s41598-022-20383-5