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Arginase: shedding light on the mechanisms and opportunities in cardiovascular diseases

Arginase, a binuclear manganese metalloenzyme in the urea, catalyzes the hydrolysis of L-arginine to urea and L-ornithine. Both isoforms, arginase 1 and arginase 2 perform significant roles in the regulation of cellular functions in cardiovascular system, such as senescence, apoptosis, proliferation...

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Detalles Bibliográficos
Autores principales: Li, Zhuozhuo, Wang, Liwei, Ren, Yuanyuan, Huang, Yaoyao, Liu, Wenxuan, Lv, Ziwei, Qian, Lu, Yu, Yi, Xiong, Yuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547100/
https://www.ncbi.nlm.nih.gov/pubmed/36209203
http://dx.doi.org/10.1038/s41420-022-01200-4