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Redefining the catalytic HECT domain boundaries for the HECT E3 ubiquitin ligase family

There are 28 unique human members of the homologous to E6AP C-terminus (HECT) E3 ubiquitin ligase family. Each member of the HECT E3 ubiquitin ligases contains a conserved bilobal HECT domain of approximately 350 residues found near their C-termini that is responsible for their respective ubiquityla...

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Detalles Bibliográficos
Autores principales: Kane, Emma I., Beasley, Steven A., Schafer, Johanna M., Bohl, Justine E., Lee, Young Sun, Rich, Kayla J., Bosia, Elizabeth F., Spratt, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547173/
https://www.ncbi.nlm.nih.gov/pubmed/36111624
http://dx.doi.org/10.1042/BSR20221036