miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia

Preeclampsia (PE) is a pregnancy-specific disorder attributed to deficient extravillous trophoblast (EVT) invasion into the uterus, but the mechanism of EVT invasion remains unclear. In this study, we found significantly elevated expression of microRNA 21 (miR21), which negatively regulates trophobl...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Mingyu, Zheng, Yangxi, Liao, Jiujiang, Wen, Li, Cheng, Juan, Huang, Jiayu, Huang, Biao, Lin, Li, Long, Yao, Wu, Yue, Ye, Xuan, Fu, Yong, Qi, Hongbo, Baker, Philip N., Tong, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547189/
https://www.ncbi.nlm.nih.gov/pubmed/36250210
http://dx.doi.org/10.1016/j.omtn.2022.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547189/
https://www.ncbi.nlm.nih.gov/pubmed/36250210
http://dx.doi.org/10.1016/j.omtn.2022.09.006

Ejemplares similares