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miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia
Preeclampsia (PE) is a pregnancy-specific disorder attributed to deficient extravillous trophoblast (EVT) invasion into the uterus, but the mechanism of EVT invasion remains unclear. In this study, we found significantly elevated expression of microRNA 21 (miR21), which negatively regulates trophobl...
Autores principales: | Hu, Mingyu, Zheng, Yangxi, Liao, Jiujiang, Wen, Li, Cheng, Juan, Huang, Jiayu, Huang, Biao, Lin, Li, Long, Yao, Wu, Yue, Ye, Xuan, Fu, Yong, Qi, Hongbo, Baker, Philip N., Tong, Chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547189/ https://www.ncbi.nlm.nih.gov/pubmed/36250210 http://dx.doi.org/10.1016/j.omtn.2022.09.006 |
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