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LOXL2-dependent deacetylation of aldolase A induces metabolic reprogramming and tumor progression()

Lysyl-oxidase like-2 (LOXL2) regulates extracellular matrix remodeling and promotes tumor invasion and metastasis. Altered metabolism is a core hallmark of cancer, however, it remains unclear whether and how LOXL2 contributes to tumor metabolism. Here, we found that LOXL2 and its catalytically inact...

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Detalles Bibliográficos
Autores principales: Jiao, Ji-Wei, Zhan, Xiu-Hui, Wang, Juan-Juan, He, Li-Xia, Guo, Zhen-Chang, Xu, Xiu-E, Liao, Lian-Di, Huang, Xin, Wen, Bing, Xu, Yi-Wei, Hu, Hai, Neufeld, Gera, Chang, Zhi-Jie, Zhang, Kai, Xu, Li-Yan, Li, En-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547286/
https://www.ncbi.nlm.nih.gov/pubmed/36209516
http://dx.doi.org/10.1016/j.redox.2022.102496