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Image-guided radiotherapy in an orthotopic mouse model of rectal cancer

Radiobiology research in rectal cancer has been limited to cell lines, patient-derived organoids (PDOs), or xenografts. Here, we describe a protocol which recapitulates more efficiently the complex contributions of the tumor microenvironment. This approach establishes a preclinical mouse model of re...

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Detalles Bibliográficos
Autores principales: Nicolas, Adele M., Pesic, Marina, Rödel, Franz, Fokas, Emmanouil, Greten, Florian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547293/
https://www.ncbi.nlm.nih.gov/pubmed/36206161
http://dx.doi.org/10.1016/j.xpro.2022.101749