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MHY4571, a novel diarylcyclohexanone derivative, exerts anti-cancer activity by regulating the PKA-cAMP-response element-binding protein pathway in squamous cell lung cancer

BACKGROUND: The protein kinase A (PKA)/cAMP response element-binding protein (CREB) has been suggested to be related to the inhibition of the proliferation of non-small cell lung cancer (NSCLC) cells. This study aimed to investigate the efficacy of a novel diarylcyclohexanone derivative, MHY4571, in...

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Detalles Bibliográficos
Autores principales: Chung, Jae Heun, Choi, Ho Jung, Kang, Yong Jung, Kim, Yun Seong, Lee, Sang-Yull, Kwon, Ryuk Jun, Jeong, Han-Sol, Park, Su-Jung, Jeong, Yeongmu, Kang, Dongwan, Ko, Jeongin, Noh, SangGyun, Chung, Hae Young, Moon, Hyung Ryong, Yoon, Seong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547450/
https://www.ncbi.nlm.nih.gov/pubmed/36209131
http://dx.doi.org/10.1186/s40164-022-00324-8