Cargando…
MHY4571, a novel diarylcyclohexanone derivative, exerts anti-cancer activity by regulating the PKA-cAMP-response element-binding protein pathway in squamous cell lung cancer
BACKGROUND: The protein kinase A (PKA)/cAMP response element-binding protein (CREB) has been suggested to be related to the inhibition of the proliferation of non-small cell lung cancer (NSCLC) cells. This study aimed to investigate the efficacy of a novel diarylcyclohexanone derivative, MHY4571, in...
Autores principales: | Chung, Jae Heun, Choi, Ho Jung, Kang, Yong Jung, Kim, Yun Seong, Lee, Sang-Yull, Kwon, Ryuk Jun, Jeong, Han-Sol, Park, Su-Jung, Jeong, Yeongmu, Kang, Dongwan, Ko, Jeongin, Noh, SangGyun, Chung, Hae Young, Moon, Hyung Ryong, Yoon, Seong Hoon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547450/ https://www.ncbi.nlm.nih.gov/pubmed/36209131 http://dx.doi.org/10.1186/s40164-022-00324-8 |
Ejemplares similares
-
MHY440, a Novel Topoisomerase Ι Inhibitor, Induces Cell Cycle Arrest and Apoptosis via a ROS-Dependent DNA Damage Signaling Pathway in AGS Human Gastric Cancer Cells
por: Jang, Jung Yoon, et al.
Publicado: (2018) -
Pro-apoptotic effect of the novel benzylidene derivative MHY695 in human colon cancer cells
por: Heo, Gwangbeom, et al.
Publicado: (2019) -
Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico
por: Bang, EunJin, et al.
Publicado: (2018) -
Design and Synthesis of (Z)-5-(Substituted benzylidene)-3-cyclohexyl-2-thioxothiazolidin-4-one Analogues as Anti-Tyrosinase and Antioxidant Compounds: In Vitro and In Silico Insights
por: Ko, Jeongin, et al.
Publicado: (2022) -
Design, Synthesis, In Vitro, and In Silico Insights of 5-(Substituted benzylidene)-2-phenylthiazol-4(5H)-one Derivatives: A Novel Class of Anti-Melanogenic Compounds
por: Yoon, Dahye, et al.
Publicado: (2023)