Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1

BACKGROUND: Although success was achieved in the therapy for a minority of advanced lung adenocarcinoma (LUAD) patients, anti-programmed death 1 (PD1) resistance was found in most LUAD patients. Here, we aimed to uncover a potential role of exosomal circular RNAs (circRNAs) in LUAD refractory to PD1...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Ao, Yong-Qiang, Zhang, Ling-Xian, Deng, Jie, Wang, Shuai, Wang, Hai-Kun, Jiang, Jia-Hao, Ding, Jian-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547453/
https://www.ncbi.nlm.nih.gov/pubmed/36209117
http://dx.doi.org/10.1186/s13046-022-02505-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547453/
https://www.ncbi.nlm.nih.gov/pubmed/36209117
http://dx.doi.org/10.1186/s13046-022-02505-z

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