Cargando…

Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1

BACKGROUND: Although success was achieved in the therapy for a minority of advanced lung adenocarcinoma (LUAD) patients, anti-programmed death 1 (PD1) resistance was found in most LUAD patients. Here, we aimed to uncover a potential role of exosomal circular RNAs (circRNAs) in LUAD refractory to PD1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Jian, Ao, Yong-Qiang, Zhang, Ling-Xian, Deng, Jie, Wang, Shuai, Wang, Hai-Kun, Jiang, Jia-Hao, Ding, Jian-Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547453/ https://www.ncbi.nlm.nih.gov/pubmed/36209117 http://dx.doi.org/10.1186/s13046-022-02505-z

Ejemplares similares

CircZNF609 as a prototype to elucidate the biological function of circRNA-mRNA interactions
por: Beltran, Manuel, et al.
Publicado: (2022)

circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation
por: Hollensen, Anne Kruse, et al.
Publicado: (2020)

CircZNF215 promotes tumor growth and metastasis through inactivation of the PTEN/AKT pathway in intrahepatic cholangiocarcinoma
por: Liao, Wenwei, et al.
Publicado: (2023)

CircATRNL1 and circZNF608 Inhibit Ovarian Cancer by Sequestering miR-152-5p and Encoding Protein
por: Lyu, Mengmeng, et al.
Publicado: (2022)

CircZNF367 promotes osteoclast differentiation and osteoporosis by interacting with FUS to maintain CRY2 mRNA stability
por: Deng, Mingsi, et al.
Publicado: (2023)

FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma
por: Shang, Qingfeng, et al.
Publicado: (2022)

circZNF91 Promotes the Malignant Phenotype of Chronic Lymphocytic Leukemia Cells by Targeting the miR-1283/WEE1 Axis
por: Li, Shaoting, et al.
Publicado: (2022)

ZNF139/circZNF139 promotes cell proliferation, migration and invasion via activation of PI3K/AKT pathway in bladder cancer
por: Yao, Jie, et al.
Publicado: (2020)

Correction for: ZNF139/circZNF139 promotes cell proliferation, migration and invasion via activation of PI3K/AKT pathway in bladder cancer
por: Yao, Jie, et al.
Publicado: (2022)

Circular RNA circZNF532 facilitates angiogenesis and inflammation in diabetic retinopathy via regulating miR-1243/CARM1 axis
por: Wang, Ting, et al.
Publicado: (2022)

Identification of a novel circular RNA circZNF652/miR-486-5p/SERPINE1 signaling cascade that regulates cancer aggressiveness in glioblastoma (GBM)
por: Liu, Liang, et al.
Publicado: (2022)

Expression of circZNF609 is Down-Regulated in Colorectal Cancer Tissue and Promotes Apoptosis in Colorectal Cancer Cells by Upregulating p53
por: Zhang, Xiaoyun, et al.
Publicado: (2019)

circZNF609 promotes the proliferation and migration of gastric cancer by sponging miR-483-3p and regulating CDK6
por: Wu, Weidong, et al.
Publicado: (2019)

Circ_ZNF778_006 promoted ESCC progression by upregulating HIF-1α expression via sponging miR-18b-5p
por: Si, Xianzhe, et al.
Publicado: (2023)

Profiling of circular RNAs in age-related cataract reveals circZNF292 as an antioxidant by sponging miR-23b-3p
por: Liang, Shuqi, et al.
Publicado: (2020)

CircZNF609 Aggravated Myocardial Ischemia Reperfusion Injury via Mediation of miR-214-3p/PTGS2 Axis
por: Tang, Wen-Qiang, et al.
Publicado: (2022)

Circular RNA circZNF566 promotes hepatocellular carcinoma progression by sponging miR-4738-3p and regulating TDO2 expression
por: Li, Shanbao, et al.
Publicado: (2020)

CircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p
por: Wang, Shengting, et al.
Publicado: (2018)

CircZNF124 regulates cell proliferation, leucine uptake, migration and invasion by miR‐199b‐5p/SLC7A5 pathway in endometrial cancer
por: Shu, Liuping, et al.
Publicado: (2021)

Circ_ZNF124 promotes non-small cell lung cancer progression by abolishing miR-337-3p mediated downregulation of JAK2/STAT3 signaling pathway
por: Li, Qianping, et al.
Publicado: (2019)

CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose‐induced apoptosis and pyroptosis by regulating the miR‐20b‐5p/STAT3 axis
por: Liang, Gao‐Hua, et al.
Publicado: (2022)

Forced Expression of ZNF143 Restrains Cancer Cell Growth
por: Izumi, Hiroto, et al.
Publicado: (2011)

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase
por: Cappadocia, Laurent, et al.
Publicado: (2015)

TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein
por: Yang, Xu, et al.
Publicado: (2022)

CircZNF609 enhances hepatocellular carcinoma cell proliferation, metastasis, and stemness by activating the Hedgehog pathway through the regulation of miR-15a-5p/15b-5p and GLI2 expressions
por: He, Yangke, et al.
Publicado: (2020)

Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma
por: Rossi, Francesca, et al.
Publicado: (2019)

Circ_0000079 Decoys the RNA-Binding Protein FXR1 to Interrupt Formation of the FXR1/PRCKI Complex and Decline Their Mediated Cell Invasion and Drug Resistance in NSCLC
por: Chen, Chen, et al.
Publicado: (2020)

Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress
por: Jiang, Xingkang, et al.
Publicado: (2016)

Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation
por: Ali, Hashim, et al.
Publicado: (2019)

circ‐ZNF609: A potent circRNA in human cancers
por: Qian, Yiguan, et al.
Publicado: (2021)

Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis
por: Dai, Weiqi, et al.
Publicado: (2023)

miR-451a Inhibits the Growth and Invasion of Osteosarcoma via Targeting TRIM66
por: Ma, Xiao, et al.
Publicado: (2019)

Alternative splicing and co-option of transposable elements: the case of TMPO/LAP2α and ZNF451 in mammals
por: Abascal, Federico, et al.
Publicado: (2015)

LncRNA BC032020 suppresses the survival of human pancreatic ductal adenocarcinoma cells by targeting ZNF451
por: Zhang, Zhipeng, et al.
Publicado: (2018)

The Functions of TRIM56 in Antiviral Innate Immunity and Tumorigenesis
por: Fu, Lin, et al.
Publicado: (2023)

Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56
por: Xue, Min, et al.
Publicado: (2019)

Identification of TRIM56 as a Potential Biomarker for Lung Adenocarcinoma
por: Lu, Kun, et al.
Publicado: (2021)

FXR agonist GW4064 enhances anti-PD-L1 immunotherapy in colorectal cancer
por: Lu, Lu, et al.
Publicado: (2023)

TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750
por: Yi, Qiyi, et al.
Publicado: (2023)

Emerging Roles of Circ-ZNF609 in Multiple Human Diseases
por: Wang, Songbo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_igoon8u6mttee2vo2trgpd84e1