Cargando…

WNT5A drives interleukin-6-dependent epithelial–mesenchymal transition via the JAK/STAT pathway in keloid pathogenesis

BACKGROUND: Keloid scarring is a fibroproliferative disease caused by aberrant genetic activation with an unclear underlying mechanism. Genetic predisposition, aberrant cellular responses to environmental factors, increased inflammatory cytokines and epithelial–mesenchymal transition (EMT) phenomena...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Young In, Shim, Jung Eun, Kim, Jihee, Lee, Won Jai, Kim, Jae Woo, Nam, Kee Hyun, Lee, Ju Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547497/
https://www.ncbi.nlm.nih.gov/pubmed/36225328
http://dx.doi.org/10.1093/burnst/tkac023