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WNT5A drives interleukin-6-dependent epithelial–mesenchymal transition via the JAK/STAT pathway in keloid pathogenesis

BACKGROUND: Keloid scarring is a fibroproliferative disease caused by aberrant genetic activation with an unclear underlying mechanism. Genetic predisposition, aberrant cellular responses to environmental factors, increased inflammatory cytokines and epithelial–mesenchymal transition (EMT) phenomena...

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Detalles Bibliográficos
Autores principales:	Lee, Young In, Shim, Jung Eun, Kim, Jihee, Lee, Won Jai, Kim, Jae Woo, Nam, Kee Hyun, Lee, Ju Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547497/ https://www.ncbi.nlm.nih.gov/pubmed/36225328 http://dx.doi.org/10.1093/burnst/tkac023

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