Slow Protein Dynamics Elicits New Enzymatic Functions by Means of Epistatic Interactions

Protein evolution depends on the adaptation of these molecules to different functional challenges. This occurs by tuning their biochemical, biophysical, and structural traits through the accumulation of mutations. While the role of protein dynamics in biochemistry is well recognized, there are limit...

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Detalles Bibliográficos
Autores principales: Rossi, Maria-Agustina, Palzkill, Timothy, Almeida, Fabio C L, Vila, Alejandro J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547502/
https://www.ncbi.nlm.nih.gov/pubmed/36136729
http://dx.doi.org/10.1093/molbev/msac194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547502/
https://www.ncbi.nlm.nih.gov/pubmed/36136729
http://dx.doi.org/10.1093/molbev/msac194

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