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Slow Protein Dynamics Elicits New Enzymatic Functions by Means of Epistatic Interactions
Protein evolution depends on the adaptation of these molecules to different functional challenges. This occurs by tuning their biochemical, biophysical, and structural traits through the accumulation of mutations. While the role of protein dynamics in biochemistry is well recognized, there are limit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547502/ https://www.ncbi.nlm.nih.gov/pubmed/36136729 http://dx.doi.org/10.1093/molbev/msac194 |