Signatures of Convergent Evolution and Natural Selection at the Alcohol Dehydrogenase Gene Region are Correlated with Agriculture in Ethnically Diverse Africans

The alcohol dehydrogenase (ADH) family of genes encodes enzymes that catalyze the metabolism of ethanol into acetaldehyde. Nucleotide variation in ADH genes can affect the catalytic properties of these enzymes and is associated with a variety of traits, including alcoholism and cancer. Some ADH vari...

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Detalles Bibliográficos
Autores principales: McQuillan, Michael A, Ranciaro, Alessia, Hansen, Matthew E B, Fan, Shaohua, Beggs, William, Belay, Gurja, Woldemeskel, Dawit, Tishkoff, Sarah A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547508/
https://www.ncbi.nlm.nih.gov/pubmed/36026493
http://dx.doi.org/10.1093/molbev/msac183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547508/
https://www.ncbi.nlm.nih.gov/pubmed/36026493
http://dx.doi.org/10.1093/molbev/msac183

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