Cargando…

Signatures of Convergent Evolution and Natural Selection at the Alcohol Dehydrogenase Gene Region are Correlated with Agriculture in Ethnically Diverse Africans

The alcohol dehydrogenase (ADH) family of genes encodes enzymes that catalyze the metabolism of ethanol into acetaldehyde. Nucleotide variation in ADH genes can affect the catalytic properties of these enzymes and is associated with a variety of traits, including alcoholism and cancer. Some ADH vari...

Descripción completa

Detalles Bibliográficos
Autores principales:	McQuillan, Michael A, Ranciaro, Alessia, Hansen, Matthew E B, Fan, Shaohua, Beggs, William, Belay, Gurja, Woldemeskel, Dawit, Tishkoff, Sarah A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Discoveries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547508/ https://www.ncbi.nlm.nih.gov/pubmed/36026493 http://dx.doi.org/10.1093/molbev/msac183

Ejemplares similares

Genetic adaptation to high altitude in the Ethiopian highlands
por: Scheinfeldt, Laura B, et al.
Publicado: (2012)

African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations
por: Fan, Shaohua, et al.
Publicado: (2019)

Correction to: African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations
por: Fan, Shaohua, et al.
Publicado: (2019)

The genetic and evolutionary basis of gene expression variation in East Africans
por: Kelly, Derek E., et al.
Publicado: (2023)

Limited Evidence for Adaptive Evolution and Functional Effect of Allelic Variation at rs702424 in the Promoter of the TAS2R16 Bitter Taste Receptor Gene in Africa
por: Campbell, Michael C., et al.
Publicado: (2014)

Genetics and geography of leukocyte telomere length in sub-Saharan Africans
por: Hunt, Steven C, et al.
Publicado: (2020)

An Empirical Test of Convergent Evolution in Rhodopsins
por: Mackin, Kristine A., et al.
Publicado: (2014)

Convergent Acquisition of Nonembryonic Development in Styelid Ascidians
por: Alié, Alexandre, et al.
Publicado: (2018)

Novelty and Convergence in Adaptation to Whole Genome Duplication
por: Bohutínská, Magdalena, et al.
Publicado: (2021)

Convergent Evolution of Ribonuclease H in LTR Retrotransposons and Retroviruses
por: Ustyantsev, Kirill, et al.
Publicado: (2015)

Repeated Evolution of Asexuality Involves Convergent Gene Expression Changes
por: Parker, Darren J, et al.
Publicado: (2019)

Additional Layer of Regulation via Convergent Gene Orientation in Yeasts
por: Gilet, Jules, et al.
Publicado: (2020)

Convergent Evolution of Hydrogenosomes from Mitochondria by Gene Transfer and Loss
por: Lewis, William H, et al.
Publicado: (2020)

Molecular Parallelism Underlies Convergent Highland Adaptation of Maize Landraces
por: Wang, Li, et al.
Publicado: (2021)

Genetic Connections and Convergent Evolution of Tropical Indigenous Peoples in Asia
por: Deng, Lian, et al.
Publicado: (2021)

Convergent Adaptation of Ootheca Formation as a Reproductive Strategy in Polyneoptera
por: Du, Erxia, et al.
Publicado: (2022)

Comparative Genomics Sheds Light on the Convergent Evolution of Miniaturized Wasps
por: Xu, Hongxing, et al.
Publicado: (2021)

Prevalent Introgression Underlies Convergent Evolution in the Diversification of Pungitius Sticklebacks
por: Wang, Yu, et al.
Publicado: (2023)

Convergent Loss of Chemoreceptors across Independent Origins of Slave-Making in Ants
por: Jongepier, Evelien, et al.
Publicado: (2021)

FADS1 and the Timing of Human Adaptation to Agriculture
por: Mathieson, Sara, et al.
Publicado: (2018)

A Genetic Mechanism for Convergent Skin Lightening during Recent Human Evolution
por: Yang, Zhaohui, et al.
Publicado: (2016)

Unmatched Level of Molecular Convergence among Deeply Divergent Complex Multicellular Fungi
por: Merényi, Zsolt, et al.
Publicado: (2020)

Convergent Evolution of Cysteine-Rich Keratins in Hard Skin Appendages of Terrestrial Vertebrates
por: Ehrlich, Florian, et al.
Publicado: (2020)

Brassica rapa Domestication: Untangling Wild and Feral Forms and Convergence of Crop Morphotypes
por: McAlvay, Alex C, et al.
Publicado: (2021)

A Phylogenomic Assessment of Processes Underpinning Convergent Evolution in Open-Habitat Chats
por: Alaei Kakhki, Niloofar, et al.
Publicado: (2022)

Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery
por: Robin, Adeline Y, et al.
Publicado: (2023)

Convergence of Domain Architecture, Structure, and Ligand Affinity in Animal and Plant RNA-Binding Proteins
por: Dias, Raquel, et al.
Publicado: (2017)

Eusociality Shapes Convergent Patterns of Molecular Evolution across Mitochondrial Genomes of Snapping Shrimps
por: Chak, Solomon T C, et al.
Publicado: (2020)

Convergent Phenotypic Evolution of Rhodopsin for Dim-Light Sensing across Deep-Diving Vertebrates
por: Xia, Yu, et al.
Publicado: (2021)

Convergent Rewiring of the Virulence Regulatory Network Promotes Adaptation of Ralstonia solanacearum on Resistant Tomato
por: Gopalan-Nair, Rekha, et al.
Publicado: (2020)

Caecilian Genomes Reveal the Molecular Basis of Adaptation and Convergent Evolution of Limblessness in Snakes and Caecilians
por: Ovchinnikov, Vladimir, et al.
Publicado: (2023)

African Suid Genomes Provide Insights into the Local Adaptation to Diverse African Environments
por: Xie, Hai-Bing, et al.
Publicado: (2022)

Principles of Cold Adaptation of Fish Lactate Dehydrogenases Revealed by Computer Simulations of the Catalytic Reaction
por: Koenekoop, Lucien, et al.
Publicado: (2023)

Resolution of Brassicaceae Phylogeny Using Nuclear Genes Uncovers Nested Radiations and Supports Convergent Morphological Evolution
por: Huang, Chien-Hsun, et al.
Publicado: (2016)

Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection
por: Zhang, Chao, et al.
Publicado: (2021)

Many Options, Few Solutions: Over 60 My Snakes Converged on a Few Optimal Venom Formulations
por: Barua, Agneesh, et al.
Publicado: (2019)

OxyR Is a Convergent Target for Mutations Acquired during Adaptation to Oxidative Stress-Prone Metabolic States
por: Anand, Amitesh, et al.
Publicado: (2020)

Tunicates Illuminate the Enigmatic Evolution of Chordate Metallothioneins by Gene Gains and Losses, Independent Modular Expansions, and Functional Convergences
por: Calatayud, Sara, et al.
Publicado: (2021)

Convergent Biochemical Pathways for Xanthine Alkaloid Production in Plants Evolved from Ancestral Enzymes with Different Catalytic Properties
por: O’Donnell, Andrew J., et al.
Publicado: (2021)

Whole-genome Comparisons Identify Repeated Regulatory Changes Underlying Convergent Appendage Evolution in Diverse Fish Lineages
por: Chen, Heidi I, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_a69pi8tg92pmsdvq5b50emrafc