Histone H3K9 demethylase JMJD2B/KDM4B promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells by regulating H3K9me2 on RUNX2

BACKGROUND: A variety of proteins including epigenetic factors are involved in the differentiation of human bone marrow mesenchymal stem cells. These cells also exhibited an epigenetic plasticity that enabled them to trans-differentiate from adipocytes to osteoblasts (and vice versa) after commitmen...

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Detalles Bibliográficos
Autores principales: Kang, Pan, Wu, Zhiming, Huang, Yuxi, Luo, Zhen, Huo, Shaochuan, Chen, Qunqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547583/
https://www.ncbi.nlm.nih.gov/pubmed/36217382
http://dx.doi.org/10.7717/peerj.13862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547583/
https://www.ncbi.nlm.nih.gov/pubmed/36217382
http://dx.doi.org/10.7717/peerj.13862

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