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Histone H3K9 demethylase JMJD2B/KDM4B promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells by regulating H3K9me2 on RUNX2
BACKGROUND: A variety of proteins including epigenetic factors are involved in the differentiation of human bone marrow mesenchymal stem cells. These cells also exhibited an epigenetic plasticity that enabled them to trans-differentiate from adipocytes to osteoblasts (and vice versa) after commitmen...
Autores principales: | Kang, Pan, Wu, Zhiming, Huang, Yuxi, Luo, Zhen, Huo, Shaochuan, Chen, Qunqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547583/ https://www.ncbi.nlm.nih.gov/pubmed/36217382 http://dx.doi.org/10.7717/peerj.13862 |
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