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Activation of Innate Immunity and Autophagy in Brain Tissues with Prion Disease and Degradation of Abnormal PrPs in Cells — China’s Studies

Unlike infectious diseases caused by conventional microbes, there are no detectable specific humoral or cellular immunoresponses to prion infection. However, extensive and active gliosis is observable in affected brain regions along with significant deposits of scrapie-like prion protein (PrP(Sc))....

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Detalles Bibliográficos
Autores principales: Chen, Cao, Shi, Qi, Xiao, Kang, Zhou, Wei, Gao, Chen, Gao, Liping, Han, Jun, Wang, Jichun, Dong, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547741/
https://www.ncbi.nlm.nih.gov/pubmed/36285112
http://dx.doi.org/10.46234/ccdcw2022.153