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Activation of Innate Immunity and Autophagy in Brain Tissues with Prion Disease and Degradation of Abnormal PrPs in Cells — China’s Studies
Unlike infectious diseases caused by conventional microbes, there are no detectable specific humoral or cellular immunoresponses to prion infection. However, extensive and active gliosis is observable in affected brain regions along with significant deposits of scrapie-like prion protein (PrP(Sc))....
Autores principales: | Chen, Cao, Shi, Qi, Xiao, Kang, Zhou, Wei, Gao, Chen, Gao, Liping, Han, Jun, Wang, Jichun, Dong, Xiaoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547741/ https://www.ncbi.nlm.nih.gov/pubmed/36285112 http://dx.doi.org/10.46234/ccdcw2022.153 |
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