Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer’s disease

Galectin-3 (Gal-3) is a beta-galactosidase binding protein involved in microglial activation in the central nervous system (CNS). We previously demonstrated the crucial deleterious role of Gal-3 in microglial activation in Alzheimer’s disease (AD). Under AD conditions, Gal-3 is primarily expressed b...

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Detalles Bibliográficos
Autores principales: Boza-Serrano, Antonio, Vrillon, Agathe, Minta, Karolina, Paulus, Agnes, Camprubí-Ferrer, Lluís, Garcia, Megg, Andreasson, Ulf, Antonell, Anna, Wennström, Malin, Gouras, Gunnar, Dumurgier, Julien, Cognat, Emmanuel, Molina-Porcel, Laura, Balasa, Mircea, Vitorica, Javier, Sánchez-Valle, Raquel, Paquet, Claire, Venero, Jose Luis, Blennow, Kaj, Deierborg, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547798/
https://www.ncbi.nlm.nih.gov/pubmed/35895141
http://dx.doi.org/10.1007/s00401-022-02469-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547798/
https://www.ncbi.nlm.nih.gov/pubmed/35895141
http://dx.doi.org/10.1007/s00401-022-02469-6

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