Identification of TMEM106B amyloid fibrils provides an updated view of TMEM106B biology in health and disease

Since the initial identification of TMEM106B as a risk factor for frontotemporal lobar degeneration (FTLD), multiple genetic studies have found TMEM106B variants to modulate disease risk in a variety of brain disorders and healthy aging. Neurodegenerative disorders are typically characterized by inc...

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Detalles Bibliográficos
Autores principales: Perneel, Jolien, Rademakers, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547799/
https://www.ncbi.nlm.nih.gov/pubmed/36056242
http://dx.doi.org/10.1007/s00401-022-02486-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547799/
https://www.ncbi.nlm.nih.gov/pubmed/36056242
http://dx.doi.org/10.1007/s00401-022-02486-5

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