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Mitochondrial event as an ultimate step in ferroptosis

In ferroptosis, the roles of mitochondria have been controversial. To explore the role of mitochondrial events in ferroptosis, we employed mitochondrial DNA-depleted ρ(0) cells that are resistant to cell death due to enhanced expression of antioxidant enzymes. Expression of mitochondrial-type GPx4 (...

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Detalles Bibliográficos
Autores principales: Oh, Soo-Jin, Ikeda, Masataka, Ide, Tomomi, Hur, Kyu Yeon, Lee, Myung-Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547870/
https://www.ncbi.nlm.nih.gov/pubmed/36209144
http://dx.doi.org/10.1038/s41420-022-01199-8