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S-nitrosylation of CSF1 receptor increases the efficacy of CSF1R blockage against prostate cancer

Sustained oxidative stress in castration-resistant prostate cancer (CRPC) cells potentiates the overall tumor microenvironment (TME). Targeting the TME using colony-stimulating factor 1 receptor (CSF1R) inhibition is a promising therapy for CRPC. However, the therapeutic response to sustained CSF1R...

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Detalles Bibliográficos
Autores principales: Firdaus, Fakiha, Kuchakulla, Manish, Qureshi, Rehana, Dulce, Raul Ariel, Soni, Yash, Van Booven, Derek J., Shah, Khushi, Masterson, Thomas, Rosete, Omar Joel, Punnen, Sanoj, Hare, Joshua M., Ramasamy, Ranjith, Arora, Himanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547886/
https://www.ncbi.nlm.nih.gov/pubmed/36209194
http://dx.doi.org/10.1038/s41419-022-05289-4