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High-throughput 3D microvessel-on-a-chip model to study defective angiogenesis in systemic sclerosis
In early systemic sclerosis (Scleroderma, SSc), the vasculature is impaired. Although the exact etiology of endothelial cell damage in SSc remains unclear, it is hypothesized that endothelial to mesenchymal transition (EndoMT) plays a key role. To perform physiologically relevant angiogenic studies,...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547891/ https://www.ncbi.nlm.nih.gov/pubmed/36209279 http://dx.doi.org/10.1038/s41598-022-21468-x |