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High-throughput 3D microvessel-on-a-chip model to study defective angiogenesis in systemic sclerosis

In early systemic sclerosis (Scleroderma, SSc), the vasculature is impaired. Although the exact etiology of endothelial cell damage in SSc remains unclear, it is hypothesized that endothelial to mesenchymal transition (EndoMT) plays a key role. To perform physiologically relevant angiogenic studies,...

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Detalles Bibliográficos
Autores principales: Kramer, Bart, Corallo, Claudio, van den Heuvel, Angelique, Crawford, Justin, Olivier, Thomas, Elstak, Edo, Giordano, Nicola, Vulto, Paul, Lanz, Henriette L., Janssen, Richard A. J., Tessari, Michela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547891/
https://www.ncbi.nlm.nih.gov/pubmed/36209279
http://dx.doi.org/10.1038/s41598-022-21468-x