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Hepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK

Nonalcoholic steatohepatitis (NASH), a common clinical disease, is becoming a leading cause of hepatocellular carcinoma (HCC). Dual specificity phosphatase 22 (DUSP22, also known as JKAP or JSP-1) expressed in numerous tissues plays essential biological functions in immune responses and tumor growth...

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Detalles Bibliográficos
Autores principales: Ge, Chenxu, Tan, Jun, Dai, Xianling, Kuang, Qin, Zhong, Shaoyu, Lai, Lili, Yi, Chao, Sun, Yan, Luo, Jing, Zhang, Chufeng, Zhu, Liancai, Wang, Bochu, Xu, Minxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547917/
https://www.ncbi.nlm.nih.gov/pubmed/36209205
http://dx.doi.org/10.1038/s41467-022-33493-5