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Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration

The microtubule (MT) plus-end binding protein Clip170 is associated closely with breast cancer invasion and migration. In this study, Clip170 tension observed by a newly designed cpstFRET tension probe was suggested to be positive related to breast cancer aggressiveness, which could be regulated by...

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Detalles Bibliográficos
Autores principales: Hu, Yunfeng, Xie, Qiu, Wu, Xiang, Liu, Weizhen, Li, DongFang, Li, Chen, Zhao, WangXing, Chen, LinLin, Zheng, Zihui, Li, GuangMing, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547975/
https://www.ncbi.nlm.nih.gov/pubmed/36209218
http://dx.doi.org/10.1038/s41419-022-05306-6