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Optical genome mapping identifies clinically relevant genomic rearrangements in prostate cancer biopsy sample

BACKGROUND: Prostate cancer (PCa) is characterized by complex genomic rearrangements such as the ETS oncogene family fusions, yet the clinical relevance is not well established. While paneled genetic tests of DNA repair genes are recommended in advanced PCa, conventional genomic or cytogenetic tools...

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Detalles Bibliográficos
Autores principales: Shim, Yeeun, Lee, Jongsoo, Seo, Jieun, Park, Cheol Keun, Shin, Saeam, Han, Hyunho, Lee, Seung-Tae, Choi, Jong Rak, Chung, Byung Ha, Choi, Young Deuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548106/
https://www.ncbi.nlm.nih.gov/pubmed/36209207
http://dx.doi.org/10.1186/s12935-022-02728-2