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Development and initial validation of a modified lymphocyte transformation test (LTT) assay in patients with DRESS and AGEP

BACKGROUND: The lymphocyte transformation test (LTT) is an in vitro assay used to diagnose drug induced hypersensitivity reactions by detecting the activation and expansion of drug-specific memory T cells to the suspected implicated drug. Traditionally radiolabelled thymidine (3H-thymidine) has been...

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Detalles Bibliográficos
Autores principales: Weir, Chris, Li, Jamma, Fulton, Richard, Fernando, Suran L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548132/
https://www.ncbi.nlm.nih.gov/pubmed/36210462
http://dx.doi.org/10.1186/s13223-022-00729-4