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Development and initial validation of a modified lymphocyte transformation test (LTT) assay in patients with DRESS and AGEP
BACKGROUND: The lymphocyte transformation test (LTT) is an in vitro assay used to diagnose drug induced hypersensitivity reactions by detecting the activation and expansion of drug-specific memory T cells to the suspected implicated drug. Traditionally radiolabelled thymidine (3H-thymidine) has been...
Autores principales: | Weir, Chris, Li, Jamma, Fulton, Richard, Fernando, Suran L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548132/ https://www.ncbi.nlm.nih.gov/pubmed/36210462 http://dx.doi.org/10.1186/s13223-022-00729-4 |
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