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Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment (SMARTT): a study protocol for a phase IV pragmatic randomized controlled patient management strategy trial

BACKGROUND: Rifampicin-resistant tuberculosis (RR-TB) remains an important global health problem. Ideally, the complete drug-resistance profile guides individualized treatment for all RR-TB patients, but this is only practised in high-income countries. Implementation of whole genome sequencing (WGS)...

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Detalles Bibliográficos
Autores principales: Van Rie, Annelies, De Vos, Elise, Costa, Emilyn, Verboven, Lennert, Ndebele, Felex, Heupink, Tim H., Abrams, Steven, Fanampe, Boitumelo, Van der Spoel Van Dyk, Anneke, Charalambous, Salome, Churchyard, Gavin, Warren, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548157/
https://www.ncbi.nlm.nih.gov/pubmed/36209235
http://dx.doi.org/10.1186/s13063-022-06793-w