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Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment (SMARTT): a study protocol for a phase IV pragmatic randomized controlled patient management strategy trial
BACKGROUND: Rifampicin-resistant tuberculosis (RR-TB) remains an important global health problem. Ideally, the complete drug-resistance profile guides individualized treatment for all RR-TB patients, but this is only practised in high-income countries. Implementation of whole genome sequencing (WGS)...
Autores principales: | Van Rie, Annelies, De Vos, Elise, Costa, Emilyn, Verboven, Lennert, Ndebele, Felex, Heupink, Tim H., Abrams, Steven, Fanampe, Boitumelo, Van der Spoel Van Dyk, Anneke, Charalambous, Salome, Churchyard, Gavin, Warren, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548157/ https://www.ncbi.nlm.nih.gov/pubmed/36209235 http://dx.doi.org/10.1186/s13063-022-06793-w |
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