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Deletion patterns, genetic variability and protein structure of pfhrp2 and pfhrp3: implications for malaria rapid diagnostic test in Amhara region, Ethiopia

BACKGROUND: Although rapid diagnostic tests (RDTs) play a key role in malaria-control strategies, their efficacy has been threatened by deletion and genetic variability of the genes pfhrp2/3. This study aims to characterize the deletion, genetic patterns and diversity of these genes and their implic...

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Detalles Bibliográficos
Autores principales: Molina - de la Fuente, Irene, Yimar, Mulat, García, Luz, González, Vicenta, Amor, Arancha, Anegagrie, Melaku, Benito, Agustín, Martínez, Javier, Moreno, Marta, Berzosa, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548178/
https://www.ncbi.nlm.nih.gov/pubmed/36209103
http://dx.doi.org/10.1186/s12936-022-04306-3