Up-regulation of miR-133a-3p promotes ovary insulin resistance on granulosa cells of obese PCOS patients via inhibiting PI3K/AKT signaling

BACKGROUND: MicroRNAs are a type of non-coding single-stranded RNA, which is involved in the regulation of ovary insulin resistance (IR). This study aims to explore the underlying mechanisms of miR-133a-3p regulating ovary IR in obese polycystic ovary syndrome (PCOS). METHODS: Granulosa cells (GCs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xiaoman, Wang, Kehua, Lang, Jiajia, Guo, Danyang, Gao, Haixia, Qiu, Yue, Jin, Xiaohan, Zhang, Mingyue, Shi, Jiaxiu, Ma, QianQian, Ma, Qian, Wen, Zixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548189/
https://www.ncbi.nlm.nih.gov/pubmed/36209087
http://dx.doi.org/10.1186/s12905-022-01994-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548189/
https://www.ncbi.nlm.nih.gov/pubmed/36209087
http://dx.doi.org/10.1186/s12905-022-01994-6

Ejemplares similares